HEXOKINASE 2 DEPLETION CONFERS SENSITIZATION TO METFORMIN AND INHIBITS GLYCOLYSIS IN LUNG SQUAMOUS CELL CARCINOMA

Hexokinase 2 Depletion Confers Sensitization to Metformin and Inhibits Glycolysis in Lung Squamous Cell Carcinoma

Lung squamous cell carcinomas (SCCs) are highly aggressive tumors, and there is currently no effective targeted therapy owing to the lack of specific mutation targets.Compared with lung adenocarcinoma (ADCs), Gaming Desk lung SCCs reportedly utilized higher levels of glucose metabolism to meet the anabolic and catabolic needs required to sustain ra

read more

Genetic characterization of the non-structural protein-3 gene of bluetongue virus serotype-2 isolate from India

Aim: Sequence analysis and phylogenetic studies based on non-structural protein-3 (NS3) gene are important in understanding the evolution and epidemiology of bluetongue virus (BTV).This study was aimed at characterizing the NS3 gene sequence of Indian BTV serotype-2 (BTV2) to elucidate its genetic relationship to global BTV isolates.Materials and M

read more